drugset / Trial / NCT07609914

A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With Migraine

NCT07609914

Phase 4 Recruiting 400 enrolled Pfizer
Non-randomizedSingle-groupOpen-labelTreatment

Summary

Acute treatments for migraine may not provide sufficient pain relief after an initial dose, and a second dose of a given medication may be needed to fully abort an attack. International Headache Society (IHS) global practice recommendations for the Acute Treatment of Migraine suggest a second dose of the same medication within the recommended dose limit in people with headache relapse after successful initial treatment of a migraine attack. The primary purpose of this study is to evaluate the safety and tolerability of redosing of rimegepant when taken for the acute treatment of a migraine attack, as it is possible that some patients may benefit from a second dose of rimegepant in this setting.

Timeline

Start
2026-05-28
Primary completion
2028-05-15
Completion
2028-05-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Rimegepant Small molecule 75 mg Oral

Indications

No indication recorded.