drugset / Trial / NCT07612787

A Multicenter Study of Belantamab Mafodotin and Mezigdomide in Patients With Relapsed Multiple Myeloma

NCT07612787

Phase 1/2 Not yet recruiting 44 enrolled University Hospital of Saint-Etienne
RandomizedParallel-groupOpen-labelTreatment

Summary

The BELAMI trial is an open label, multicenter, phase 2 study for patients with MM who relapsed following BCMA-directed CAR-T cells or bispecific antibodies with a Phase Ib Safety run-in. The primary hypothesis of this study is that a combination of ADC targeting BCMA and CELMoD will be efficient for these patients.

Timeline

Start
2026-06-01
Primary completion
2028-01-01
Completion
2031-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Belantamab mafodotin Monoclonal antibody
Subject Mezigdomide Small molecule Oral

Indications