drugset / Trial / NCT07613450

A Phase III Study of SYHA1813 for Recurrent or Progressive High-Grade Meningiomas

NCT07613450

Phase 3 Not yet recruiting 136 enrolled Shanghai Runshi Pharmaceutical Technology Co., Ltd
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a randomized, controlled, open-label, multicenter, Phase III clinical study designed to compare the efficacy and safety of SYHA1813 versus treatment of investigators' choice in patients with recurrent or progressive high-grade meningioma not amenable to local therapy.

Timeline

Start
2026-05-20
Primary completion
2029-07-31
Completion
2029-10-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody
Subject Hydroxyurea Other / unclassified
Subject SYHA1813 Unknown 20 mg
Subject Temozolomide Small molecule

Indications