drugset / Trial / NCT07619235

A Single-arm, Multicenter Clinical Study of Iparomlimab and Toripalimab in Combination With Bevacizumab and Chemotherapy as First-line Treatment for Advanced Biliary Tract Cancer

NCT07619235

Phase 4 Not yet recruiting 32 enrolled Xianglin Yuan
NaSingle-groupOpen-labelTreatment

Summary

This is a single-arm, multicenter clinical study designed to evaluate the efficacy and safety of Iparomlimab and Toripalimab (QL1706) in combination with bevacizumab and chemotherapy as first-line treatment for patients with advanced biliary tract cancer

Timeline

Start
2026-07-01
Primary completion
2028-07-01
Completion
2028-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 7.5 mg/kg Intravenous
Subject Cisplatin Other / unclassified 25 mg/m2 Intravenous
Subject Gemcitabine Small molecule 1000 mg/m2 Intravenous
Subject Iparomlimab Monoclonal antibody 7.5 mg/kg Intravenous
Subject Toripalimab Monoclonal antibody 7.5 mg/kg Intravenous

Indications