drugset / Trial / NCT07620392

An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants With Rheumatoid Arthritis

NCT07620392

Phase 2 Recruiting 120 enrolled Hoffmann-La Roche
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The study will evaluate the long-term safety and efficacy of Afimkibart (also known as RO7790121) in participants with moderate to severe Rheumatoid Arthritis (RA) who have an inadequate response or intolerance to tumor necrosis factor (TNF) and/or Janus kinase (JAK) inhibitors, and who were previously treated with Afimkibart.

Timeline

Start
2026-06-03
Primary completion
2033-07-08
Completion
2033-07-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Afimkibart Monoclonal antibody Subcutaneous

Indications