drugset / Trial / NCT07621107

Effect of Guanxinning Tablet on Coronary Microcirculation After Primary Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction

NCT07621107 ↗

Phase 2 Not yet recruiting 70 enrolled Beijing Anzhen Hospital
RandomizedParallel-groupQuadruple-blindTreatment

Summary

①Research objective: In a small sample population, through the pre - experimental method, explore and evaluate the effect of Guanxinning tablets on the coronary microcirculation after primary percutaneous coronary intervention (PPCI) in patients with acute ST - segment elevation myocardial infarction (STEMI), with the change in the percentage of intramyocardial hemorrhage (IMH) in ventricular mass measured by cardiac magnetic resonance (CMR) imaging as the primary endpoint. ②Research significance: The research results of this project will provide preliminary theoretical basis and methodological support for the formal randomized controlled study on evaluating the effect of Guanxinning tablets on the coronary microcirculation after PPCI in STEMI patients. It will offer new ideas for the long - term clinical treatment of STEMI patients after PPCI, and provide important theoretical support for expanding the clinical indications of Guanxinning tablets and exploring the reasons for its improvement of cardiovascular outcomes.

Timeline

Start
2026-06-01
Primary completion
2027-01-01
Completion
2027-02-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Guanxinning Tablets (2015) Unknown 4 unknown —