drugset / Trial / NCT07623356
A Study of AK138D1 Alone or in Combination With Ivonescimab in Advanced Non-Small Cell Lung Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
The goal of this clinical trial is to evaluate the safety, tolerability, and efficacy of AK138D1 as monotherapy or in combination with ivonescimab in patients with advanced non-small cell lung cancer. Participants will receive study treatment with AK138D1 alone or in combination with ivonescimab, undergo safety assessments and tumor evaluations, and be followed for treatment tolerability, antitumor activity, and clinical outcomes.
Timeline
- Start
- 2026-06-18
- Primary completion
- 2028-06-18
- Completion
- 2030-07-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | AK138D1 | Unknown | — | Intravenous |
| Subject | Carboplatin | Small molecule | — | Intravenous |
| Subject | Ivonescimab | Monoclonal antibody | — | Intravenous |