drugset / Trial / NCT07634068
Vertebrobasilar Dolichoectasia Treatment With Amiloride
NaSingle-groupOpen-labelTreatment
Summary
The aim of this pilot study is to assess the efficacy of amiloride in reducing wall enhancement in vertebrobasilar dolichoectasia(VBD) on high-resolution magnetic resonance vessel wall imaging(HR-VWI) via anti-inflammatory mechanisms, clarify the efficacy of amiloride in delaying the progression of VBD, evaluate the safety of amiloride in the treatment of VBD.
Timeline
- Start
- 2026-06
- Primary completion
- 2027-06
- Completion
- 2027-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Amiloride | Small molecule | 2.5 mg | Oral |
| Subject | Hydrochlorothiazide | Unknown | 25 mg | Oral |