drugset / Trial / NCT07635914

A Study Evaluating Aprocitentan Tablets(SYH9108) for the Treatment of Resistant Hypertension

NCT07635914

Phase 3 Not yet recruiting 382 enrolled CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Aprocitentan tablets are currently the only endothelin dual receptor antagonist approved internationally for the treatment of resistant hypertension.This is a multicenter, randomized, double-blind, placebo-controlled Phase 3 study to evaluate the efficacy and safety of aprocitentan tablets(SYH9108) in patients with treatment-resistant hypertension (rHTN)

Timeline

Start
2026-05-31
Primary completion
2029-12-28
Completion
2030-05-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Aprocitentan Small molecule Oral