drugset / Trial / NCT07638852

Study of Radiotherapy Combined With Platinum, Adebrelimab and Bevazumab in the Treatment of TNBC-BM.

NCT07638852 ↗

Phase 2 Recruiting 58 enrolled Fudan University
RandomizedCrossoverOpen-labelTreatment

Summary

This is an open-label, prospective, single-arm, multicenter phase II clinical trial. The aim is to explore the efficacy and safety of radiotherapy combined with cisplatin/carboplatin, adebrelimab, and bevacizumab in patients with triple-negative breast cancer and brain metastases.

Timeline

Start
2026-02-02
Primary completion
2028-06-30
Completion
2028-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Adebrelimab Monoclonal antibody — —
Subject Bevacizumab Monoclonal antibody — —
Subject Carboplatin Small molecule — —
Subject Cisplatin Other / unclassified — —