drugset / Trial / NCT07640061

Pilot Studies Testing the Use of Oral Amitriptyline in Reducing Localized Burn Injury-induced Microvesicle Particle Release

NCT07640061

Phase 1 Not yet recruiting 20 enrolled Wright State University
RandomizedCrossoverDouble-blindPrevention

Summary

The purpose of this study is to determine the amount of substances contained in skin known as microvesicle particles (MVP). The hypothesis to be tested in this study is that treatment with a single dose of 75mg of amitriptyline will block the MVP released from the skin from a very small localized burn injury.

Timeline

Start
2027-06
Primary completion
2033-06
Completion
2033-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Amitriptyline Small molecule 75 mg Oral

Indications

No indication recorded.