drugset / Trial / NCT07645690

The Safety and Efficacy of Allogeneic CD70 CAR-T Therapy in Unresectable or Metastatic Clear Cell Renal Cell Carcinoma

NCT07645690 ↗

Phase 0 Recruiting 30 enrolled Chinese PLA General Hospital
NaSingle-groupOpen-labelTreatment

Summary

CLEAR CAR-T cell injection (ET-970) is an engineered CD70-targeting allogeneic Chimeric Antigen Receptor T-Cell (CAR-T cell). This is a multi-center, single-arm, open-label, early exploratory clinical study. The objective of this study is to evaluate the safety and preliminary efficacy of ET-970 in unresectable or metastatic clear cell renal cell carcinoma.

Timeline

Start
2026-07-01
Primary completion
2027-12-31
Completion
2028-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject ET-970 Cell therapy — Intravenous