drugset / Trial / NCT07648472
A Study of the Safety and Efficacy of the Intravenous and Intratumoral Injection of OVV-01 in Patients With Advanced Solid Tumours.
Phase 1
Recruiting
18 enrolled
Joint Biosciences Ltd.
Cancer Institute and Hospital, Chinese Academy of Medical Sciences · collab
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This is an open-label, single-arm, dose escalation clinical study to evaluate the safety and preliminary efficacy of OVV-01 Injection in patients with advanced solid tumors, following both intravenous (iv.) and intratumoral (it.) injections. This study consists of two parts: Part 1 is a dose escalation study of iv. administration; Part 2 is a dose escalation study of iv. and it. administration.
Timeline
- Start
- 2026-04-21
- Primary completion
- 2027-04-20
- Completion
- 2027-04-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | OVV-01 | Unknown | 6e+10 unknown | Intravenous |
| Comparator | OVV-01 | Unknown | 6e+11 unknown | Intravenous |