drugset / Trial / NCT07653282
Effect of GnRH Agonist in FET
Phase 1/2
Not yet recruiting
122 enrolled
Assiut University
Woman's Health University Hospital, Egypt · collab
RandomizedParallel-groupSingle-blindOther
Summary
To evaluate the impact of single dose GnRH agonist administration as luteal phase support on pregnancy outcomes in frozen ICSI cycle
Timeline
- Start
- 2026-08-01
- Primary completion
- 2027-08-01
- Completion
- 2028-08-01
Publications
- Results Liu Y, Huang K, Chen C, Wen L, Lei M, Guo Y, Tang B. Effect of luteal-phase GnRH agonist on frozen-thawed embryo transfer during artificial cycles: a randomised clinical pilot study. Front Endocrinol (Lausanne). 2023 Jun 9;14:1098576. doi: 10.3389/fendo.2023.1098576. eCollection 2023.
- Results Li S, Li Y. Administration of a GnRH agonist during the luteal phase frozen-thawed embryo transfer cycles: a meta-analysis. Gynecol Endocrinol. 2018 Nov;34(11):920-924. doi: 10.1080/09513590.2018.1480714. Epub 2018 Jul 11.
- Results Chang WS, Lin PH, Li CJ, Chern CU, Chen YC, Lin LT, Tsui KH. Additional single dose GnRH agonist during luteal phase support may improve live birth rate in GnRHa-HRT frozen-thawed embryo transfer cycle: a retrospective cohort study. BMC Pregnancy Childbirth. 2023 Mar 14;23(1):174. doi: 10.1186/s12884-023-05491-y.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Triptorelin | Other / unclassified | 0.1 mg | Subcutaneous |
Indications
No indication recorded.