drugset / Trial / NCT07653438
In Vivo Fluorescence Molecular Bronchoscopy of Durvalumab-680LT in Patients With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) After Chemoradiotherapy
Non-randomizedSequentialOpen-labelDiagnostic
Summary
PulmoPrint is a clinical study at the University Medical Center Groningen (UMCG) that investigates why some patients with unresectable stage III lung cancer don't respond to immunotherapy after chemoradiotherapy. To do this, a small dose of a fluorescently labeled version of the immunotherapy drug durvalumab is given via an intravenous (IV) drip, after which a bronchoscopy is performed to visualize where and how much of the drug reaches the tumor and lymph nodes - before the actual durvalumab treatment starts.
Timeline
- Start
- 2026-09-01
- Primary completion
- 2028-03-01
- Completion
- 2031-03-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | durvalumab-680LT | Diagnostic / imaging agent | 15 mg | Intravenous |
| Subject | durvalumab-680LT | Diagnostic / imaging agent | 25 mg | Intravenous |