drugset / Trial / NCT07654465

Rituximab Maintenance Versus Observation After R2 Induction in Previously Untreated Marginal Zone Lymphoma

NCT07654465

Phase 2 Not yet recruiting 144 enrolled Sun Yat-sen University
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a multicenter, phase 2, randomized trial to compare rituximab maintenance with observation after rituximab and lenalidomide (R2) induction therapy in patients with previously untreated marginal zone lymphoma. Patients who achieve complete response or partial response after R2 induction will be randomized to receive rituximab maintenance or observation.

Timeline

Start
2026-07
Primary completion
2030-07
Completion
2031-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Rituximab Monoclonal antibody