drugset / Trial / NCT07661108

A Clinical Study of MK-8527 in Healthy Participants (MK-8527-021)

NCT07661108

Phase 1 Recruiting 44 enrolled Merck Sharp & Dohme LLC
RandomizedCrossoverOpen-labelBasic science

Summary

Researchers are studying a medicine called MK-8527 to learn how it behaves in the body of healthy adults. The goal of this study is to learn about the effect of MK-8527 when it is taken with food or with other medicines. Researchers also want to learn about the safety of MK-8527 and if people tolerate it. Tolerate means participants will receive treatment in the trial unless they need to stop it due to health problems.

Timeline

Start
2026-06-30
Primary completion
2026-10-09
Completion
2026-10-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Itraconazole Small molecule Oral
Subject MK-8527 Small molecule Oral
Subject Probenecid Small molecule Oral

Indications

No indication recorded.