drugset / Trial / NCT07662473

The Efficacy and Safety of Trastuzumab Deruxtecan in Advanced or Metastatic NSCLC With HER2 Over Expression

NCT07662473

Phase 2 Not yet recruiting 30 enrolled Hunan Province Tumor Hospital
NaSingle-groupOpen-labelTreatment

Summary

This is a single arm, multicenter and prospective study to evaluate the efficacy and safety of T-DXd for the treatment in locally advanced, unresectable, or metastatic participants with selected HER2 positive (IHC 3+) NSCLC which are not eligible for curative therapy

Timeline

Start
2026-07-29
Primary completion
2027-12-31
Completion
2028-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Trastuzumab deruxtecan Monoclonal antibody 5.4 mg/kg Intravenous