drugset / Trial / NCT07664527

Novel Method for Removal of Orally Deposited Inhaled Fluticasone Propionate

NCT07664527

Phase 4 Not yet recruiting 20 enrolled University of Wisconsin, Madison
RandomizedCrossoverOpen-labelTreatment

Summary

This study is to find out if an Extra Virgin Olive-Oil-based Water (EVOOW) mix, removes more Fluticasone Propionate (FP) from the mouth than Water alone. 2 strengths of the EVOOW mix will be tested, one with equal parts EVOO and Water (50/50) and one with 3 parts EVOO and 1 part Water (75/25). Removing more FP deposits may help decrease the risk for obstructive sleep apnea (OSA), candidiasis (thrush), and speech and swallow dysfunction. Participants will be on study for up to 3 weeks.

Timeline

Start
2026-07
Primary completion
2027-04
Completion
2027-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Fluticasone propionate Other / unclassified 220 ug Inhaled

Indications