drugset / Trial / NCT07669415

A Study of LM-168 Combined With Other Anti-tumor Treatments in Participants With Advanced Solid Tumors

NCT07669415

Phase 2 Not yet recruiting 108 enrolled LaNova Medicines Limited
Non-randomizedSequentialOpen-labelTreatment

Summary

For Safety introduction phase,this study is to evaluate the safety and tolerability of LM-168 in combination with other anti-tumor treatment regimens in participants of advanced solid tumor trials, determine the maximum tolerated dose (MTD), and explore the recommended phase II dose (RP2D). For Dose expansion phase,this study is to evaluate the preliminary antitumor activity of LM-168 in combination with other antitumor treatment regimens in participants of advanced solid tumor trials, measured by objective response rate (ORR)

Timeline

Start
2026-06-30
Primary completion
2027-12-15
Completion
2028-12-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Docetaxel Small molecule Intravenous
Subject LM-168 Unknown Intravenous
Subject Tislelizumab Monoclonal antibody Intravenous

Indications