drugset / Trial / NCT07669610
An Open-Label, Randomized Phase III Study of Trastuzumab Rezetecan With or Without Bevacizumab in First to Third Line BLIS Subtype TNBC
RandomizedParallel-groupOpen-labelTreatment
Summary
This study is a prospective, open-label, phase III, randomized controlled clinical trial. It is planned to screen patients with inoperable locally advanced or metastatic triple-negative breast cancer of the BLIS subtype. A total of 140 patients are planned to be enrolled.
Timeline
- Start
- 2026-10-01
- Primary completion
- 2028-09-30
- Completion
- 2029-03-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bevacizumab | Monoclonal antibody | 15 mg/kg | Intravenous |
| Comparator | Trastuzumab Rezetecan | Monoclonal antibody | 4.8 mg/kg | Intravenous |