drugset / Trial / NCT07669610

An Open-Label, Randomized Phase III Study of Trastuzumab Rezetecan With or Without Bevacizumab in First to Third Line BLIS Subtype TNBC

NCT07669610

Phase 3 Not yet recruiting 140 enrolled Fudan University
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is a prospective, open-label, phase III, randomized controlled clinical trial. It is planned to screen patients with inoperable locally advanced or metastatic triple-negative breast cancer of the BLIS subtype. A total of 140 patients are planned to be enrolled.

Timeline

Start
2026-10-01
Primary completion
2028-09-30
Completion
2029-03-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 15 mg/kg Intravenous
Comparator Trastuzumab Rezetecan Monoclonal antibody 4.8 mg/kg Intravenous