drugset / Trial / NCT07670416

A Study to Evaluate the Effects of Enicepatide in Participants With Obesity or Overweight, With or Without Type 2 Diabetes

NCT07670416 ↗

Phase 3 Recruiting 300 enrolled Hoffmann-La Roche
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to assess the efficacy and safety of enicepatide, a dual glucagon-like peptide-1 (GLP-1)/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist (RA) being developed for chronic weight management, as an adjunct to a reduced-calorie diet and increased physical activity in participants without Type 2 diabetes mellitus (T2DM) who have obesity or overweight with at least one weight-related comorbidity, and in participants with T2DM who have obesity or overweight.

Timeline

Start
2026-07-03
Primary completion
2028-02-24
Completion
2028-03-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Enicepatide Unknown — Subcutaneous