drugset / Trial / NCT07673549

Efficacy and Safety of Oral Antiviral Therapy for Idiopathic Trigeminal Neuralgia

NCT07673549

RandomizedParallel-groupOpen-labelTreatment

Summary

This is a multicenter, prospective, randomized, controlled trial. A total of 165 patients with idiopathic trigeminal neuralgia will be enrolled and randomly divided into three groups at a 1:1:1 ratio. The aim is to compare the efficacy and safety of conventional carbamazepine monotherapy, carbamazepine combined with oral antiviral therapy, and carbamazepine combined with anti-inflammatory therapy in pain relief, quality of life improvement and adverse event profiles.

Timeline

Start
2026-08-31
Primary completion
2027-12-31
Completion
2027-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Acyclovir Small molecule 800 mg Oral
Subject Carbamazepine Small molecule 600 mg
Subject Celecoxib Other / unclassified 200 mg

Indications