drugset / Trial / NCT07673549
Efficacy and Safety of Oral Antiviral Therapy for Idiopathic Trigeminal Neuralgia
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a multicenter, prospective, randomized, controlled trial. A total of 165 patients with idiopathic trigeminal neuralgia will be enrolled and randomly divided into three groups at a 1:1:1 ratio. The aim is to compare the efficacy and safety of conventional carbamazepine monotherapy, carbamazepine combined with oral antiviral therapy, and carbamazepine combined with anti-inflammatory therapy in pain relief, quality of life improvement and adverse event profiles.
Timeline
- Start
- 2026-08-31
- Primary completion
- 2027-12-31
- Completion
- 2027-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acyclovir | Small molecule | 800 mg | Oral |
| Subject | Carbamazepine | Small molecule | 600 mg | — |
| Subject | Celecoxib | Other / unclassified | 200 mg | — |