drugset / Trial / NCT07673900

Semaglutide Delivered Epi-Intradermally by Microarray Patch (VX-201) Versus Subcutaneous Administration in Healthy Overweight and Obese Participants

NCT07673900

Phase 1 Recruiting 62 enrolled Terrestrial Bio, Inc. Celerion · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

VX-201-101 is a first-in-human Phase 1 clinical study evaluating VX-201, a needle-free microneedle (MN) array patch (MAP) that delivers semaglutide through the skin as an alternative to subcutaneous (SC) injection.

Timeline

Start
2026-06-15
Primary completion
2027-02-10
Completion
2027-05-18

Drugs

EvaluationDrugModalityDoseRoute
Comparator Semaglutide Peptide 0.25 mg Other
Comparator Semaglutide Peptide 0.5 mg Other
Comparator Semaglutide Peptide 2.4 mg Other

Indications