drugset / Trial / NCT07677878

Blinatumomab Combined With Low-dose DLI as Maintenance Therapy After Transplantation for B-ALL

NCT07677878

Phase 1 Recruiting 60 enrolled Liping Dou
NaSingle-groupOpen-labelPrevention

Summary

This prospective study will be conducted in high-risk B-ALL patients post-allo-HSCT. We propose to investigate the safety and therapeutic efficacy of blinatumomab plus low-dose DLI maintenance therapy, with the ultimate goal of enhancing long-term survival outcomes.

Timeline

Start
2024-12-01
Primary completion
2028-11-30
Completion
2028-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Blinatumomab Monoclonal antibody 28 ug