drugset / Trial / NCT07693153

The Effects of Psilocybin on Social Connectedness

NCT07693153

Phase 1 Not yet recruiting 51 enrolled Yale University
RandomizedParallel-groupTriple-blindOther

Summary

The study is a randomized, double-blind, placebo-controlled, expectancy-controlled, mechanistic trial. This study looks to explore whether a single dose of psilocybin (25mg) reduces amygdala reactivity to negative socioemotional stimuli during the Facial Emotion Recognition Task (FERT) compared to a placebo in adults who feel lonely or those with unresolved grief symptoms.

Timeline

Start
2026-08-31
Primary completion
2031-12-15
Completion
2031-12-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Psilocybin Other / unclassified 25 mg

Indications

No indication recorded.