drugset / Trial / NCT07694024

Efficacy of 1% Nanochitosan Solution in the Treatment of Denture Stomatitis

NCT07694024

Phase 2 Completed 30 enrolled Kerman University of Medical Sciences
RandomizedParallel-groupSingle-blindTreatment

Summary

The purpose of this study is to evaluate and compare the clinical efficacy of a 1% nanochitosan solution versus a standard Nystatin oral suspension in patients diagnosed with Newton's type II denture stomatitis (chronic atrophic candidiasis). Chitosan nanoparticles are investigated as a potential biocompatible, mucoadhesive alternative to traditional antifungal treatments to accelerate mucosal healing and reduce the erythema of the palatal mucosa.

Timeline

Start
2016-01-17
Primary completion
2016-05-04
Completion
2016-05-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Nanochitosan Unknown 2 ml Topical
Comparator Nystatin Unknown 2 ml Topical