drugset / Trial / NCT07694024
Efficacy of 1% Nanochitosan Solution in the Treatment of Denture Stomatitis
RandomizedParallel-groupSingle-blindTreatment
Summary
The purpose of this study is to evaluate and compare the clinical efficacy of a 1% nanochitosan solution versus a standard Nystatin oral suspension in patients diagnosed with Newton's type II denture stomatitis (chronic atrophic candidiasis). Chitosan nanoparticles are investigated as a potential biocompatible, mucoadhesive alternative to traditional antifungal treatments to accelerate mucosal healing and reduce the erythema of the palatal mucosa.
Timeline
- Start
- 2016-01-17
- Primary completion
- 2016-05-04
- Completion
- 2016-05-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nanochitosan | Unknown | 2 ml | Topical |
| Comparator | Nystatin | Unknown | 2 ml | Topical |