drugset / Trial / NCT07694427

Mo-Rez in First- Line (1L) Maintenance Treatment of Non- Homologous Recombination Deficient Ovarian Cancer (HRd OC) [BEHOLD-Ovarian03]

NCT07694427

Phase 3 Not yet recruiting 720 enrolled GlaxoSmithKline ENGOT, GOG, APGOT · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

This study specifically aims to evaluate how well mocertatug rezetecan (Mo-Rez) alone or in combination with bevacizumab works in treating ovarian cancer compared to bevacizumab alone or active observation (AO). The study also assesses whether Mo-Rez is safe and tolerated well by participants in comparison to bevacizumab alone OR AO and will help provide a better understanding of the main side effects of the drugs.

Timeline

Start
2026-10-09
Primary completion
2029-09-06
Completion
2032-11-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody
Subject Mocertatug rezetecan Unknown

Indications