drugset / Trial / NCT07694700
Colistin and Meropenem Versus Amikacin and Meropenem for MDR Gram Negative Bacteria Regarding Efficacy and Safety.
RandomizedParallel-groupOpen-labelTreatment
Summary
Objective of this study is to compare the efficacy and safety between combination of colistin and meropenem and combination of amikacin and meropenem for multi-drug-resistant gram-negative bacteria in Intensive Care Unit. In Beni- Suef University Hospital.
Timeline
- Start
- 2025-12-30
- Primary completion
- 2026-08-30
- Completion
- 2026-09-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amikacin | Small molecule | 15 mg/kg | Intravenous |
| Comparator | Amikacin | Small molecule | 30 mg/kg | Intravenous |
| Comparator | Colistimethate | Unknown | 2.5 mg/kg | Intravenous |
| Comparator | Colistimethate | Unknown | 5 mg/kg | Intravenous |
| Comparator | Meropenem | Small molecule | 2 g | Intravenous |