drugset / Trial / NCT07695285

Lemborexant Use for Cognition Improvement in Postoperative Delirium in Elderly Patients: A Randomized Controlled Trial

NCT07695285

Phase 2 Not yet recruiting 992 enrolled Beijing Tiantan Hospital
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This prospective, randomized controlled trial aims to investigate the perioperative use of lemborexant, an orexin receptor antagonist, for reducing postoperative delirium (POD) in elderly patients undergoing general anesthesia.

Timeline

Start
2026-09-01
Primary completion
2029-09-01
Completion
2029-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Lemborexant Small molecule

Indications