drugset / Trial / NCT07697586

SKB264 in Combination With SKB118 for Non-Small Cell Lung Cancer

NCT07697586

Phase 2 Not yet recruiting 206 enrolled Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
NaSingle-groupOpen-labelTreatment

Summary

This is an open-label, multi-center, Phase II clinical study to evaluate the safety, tolerability, and efficacy of SKB264 in combination with SKB118 in participants with NSCLC. The study includes a dose escalation phase and an expansion phase.

Timeline

Start
2026-08
Primary completion
2028-08
Completion
2029-08

Drugs

EvaluationDrugModalityDoseRoute
Subject SKB118 Unknown 3 mg/kg Intravenous
Subject SKB118 Unknown 10 mg/kg Intravenous
Subject SKB118 Unknown 20 mg/kg Intravenous
Subject Sacituzumab Tirumotecan Other / unclassified 4 mg/kg Intravenous