drugset / Trial / NCT07698626

Venlafaxine Combined With Education and Behavioral Intervention for Bladder Pain Syndrome

NCT07698626

Phase 1 Not yet recruiting 140 enrolled Beijing Tiantan Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

This study aims to compare two treatment plans for adults with bladder pain syndrome (also called interstitial cystitis), a disease that causes long-lasting bladder pain, frequent urination and urgent need to pee. All participants will receive standardized patient education and behavioral training to relieve urinary discomfort. Half of the participants will only get this behavioral intervention, while the other half will take oral venlafaxine in addition to the same behavioral training for 12 weeks. We will check patients' pain levels, urination frequency, sleep quality, mood and daily life ability at 1, 2, 6 and 12 weeks of treatment. The main goal is to see whether adding venlafaxine can better ease bladder pain and urinary symptoms without obvious side effects. This research will provide safer and more effective treatment suggestions for patients with bladder pain syndrome.

Timeline

Start
2026-12-31
Primary completion
2027-12-30
Completion
2027-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Venlafaxine Small molecule 225 mg Oral