drugset / Trial / NCT07704957
A Randomized Controlled Trial of Doxycycline Post Exposure Prophylaxis to Prevent Incident Bacterial STIs Among Women in the United States
Phase 4
Not yet recruiting
519 enrolled
Tulane University
Louisiana State University Health Sciences Center in New Orleans · collabNational Institute of Allergy and Infectious Diseases (NIAID) · collabUniversity of Alabama at Birmingham · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The bacterial sexually transmitted infections (STIs) chlamydia, gonorrhea, and syphilis cause multiple adverse outcomes in women, and prevention strategies are critically needed. This project will determine the efficacy of doxycycline post-exposure prophylaxis (doxy PEP) to prevent STIs among women through a phase IV, open-label, randomized controlled trial.
Timeline
- Start
- 2027-01-01
- Primary completion
- 2031-02-28
- Completion
- 2032-04-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Doxycycline | Small molecule | 200 mg | Oral |