drugset / Trial / NCT07708428
An Open-Label PET/CT Imaging Study to Evaluate Brain Serotonin Transporter (SERT) Occupancy Following Single-Dose Administration of LG-0317 Tablets in Healthy Participants
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The purpose of the study is to evaluate brain serotonin transporter (SERT) receptor occupancy (RO) following single oral doses of LG-0317 tablets in healthy male participants; and to explore the pharmacokinetic/pharmacodynamic (PK/PD) relationship between LG-0317 plasma concentrations and SERT occupancy..
Timeline
- Start
- 2026-07-24
- Primary completion
- 2026-09-30
- Completion
- 2027-02-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | LG-0317 | Unknown | 20 mg | Oral |
| Subject | LG-0317 | Unknown | 40 mg | Oral |
| Subject | LG-0317 | Unknown | 80 mg | Oral |
Indications
No indication recorded.