drugset / Trial / NCT07729137

Study of EO2002 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction

NCT07729137 ↗

Phase 2 Recruiting 121 enrolled Emmecell
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study will evaluate the safety and effectiveness of a single injection of EO2002 at one of two dose levels (150,000 or 500,000 magnetic human corneal endothelial cells \[mHCECs\]), compared with a placebo injection, in participants with corneal edema caused by corneal endothelial dysfunction.

Timeline

Start
2026-10
Primary completion
2027-08
Completion
2028-02

Drugs

EvaluationDrugModalityDoseRoute
Subject EO2002 Cell therapy 150000 cells Other
Subject EO2002 Cell therapy 500000 cells Other