drugset / Trial / NCT07751848

A Study of Outcomes in Chinese Patients Treated With Anifrolumab Who Have Active Mod-severe Systemic Lupus Erythematosus

NCT07751848 ↗

Phase 3 Recruiting 417 enrolled AstraZeneca
NaSingle-groupOpen-labelTreatment

Summary

This study aims to describe clinical outcomes, with focus on remission, achieved with use of anifrolumab participants with SLE on standard-of-care (as recommended by 2025 China SLE guidelines). Further, it aims to describe outcomes alongside a systematic approach to glucocorticoid (GC) tapering, in terms of effectively minimising GC use, as well as discontinuing GC use, thereby reducing GC exposure.

Timeline

Start
2026-08-31
Primary completion
2028-08-25
Completion
2028-08-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Anifrolumab Monoclonal antibody — Intravenous