drugset / Trial / NCT07753811
Effect of Oral Isotretinoin on Ocular Surface and Meibomian Glands
Non-randomizedParallel-groupOpen-labelHealth-services research
Summary
The aim of the study was to evaluate meibomian gland morphology using non-contact meibography and ocular surface changes in patients with acne vulgaris treated with isotretinoin as indicators of dry eye, which is known to be a side effect of isotretinoin.
Timeline
- Start
- 2024-01-01
- Primary completion
- 2025-01-01
- Completion
- 2025-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Isotretinoin | Other / unclassified | 0.1 mg/kg | Oral |
| Comparator | Isotretinoin | Other / unclassified | 0.4 mg/kg | Oral |