5-Fluorouracil and Calcipotriene for Field Treatment of Actinic Keratoses

Summary

Combination field therapy with 5-fluorouracil and calcipotriene (5FU/C) has become standard of care among dermatologists for the field treatment of diffuse actinic keratoses (AKs). Data suggest that the addition of calcipotriene elicits a sustained T cell memory allowing for both short and long-term AK clearance. Our objective is to evaluate the efficacy, as well as, document the timing, severity and duration of local cutaneous reactions to topical treatment with 5FU/C for the treatment of AKs.

Timeline

Start

2026-09

Primary completion

2027-09

Completion

2027-09

Drugs

Indications