drugset / Trial / NCT07795073

Acceleration of Tooth Movement Using PRP and Photobiomodulation With Clear Aligners

NCT07795073 ↗

Phase 1/2 Not yet recruiting 42 enrolled Sana'a University
RandomizedParallel-groupSingle-blindTreatment

Summary

This study compares the effectiveness of two adjunct therapies- photobiomodulation (low-level laser therapy) (PBM) and localized platelet-rich plasma (PRP) injections in accelerating orthodontic tooth movement. Participants receiving clear aligner therapy will be randomly assigned to one of three groups: clear aligners with PBM, clear aligners with PRP, or clear aligners alone (control group). The goal is to evaluate the efficiency, tooth movement tracking and safety.

Timeline

Start
2026-09-01
Primary completion
2027-04-01
Completion
2027-05-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Platelet Rich Plasma Other / unclassified — Other

Indications

No indication recorded.