drugset / Trial / NCT07797478

A Study of RO7890597 in Healthy Adult Volunteers

NCT07797478 ↗

Phase 1 Recruiting 139 enrolled Genentech, Inc.
RandomizedSequentialDouble-blindBasic science

Summary

This study will evaluate the safety, pharmacokinetics (PK), and activity of single and multiple doses of RO7890597 compared with placebo in healthy volunteers. The study includes single ascending dose (SAD) stage, multiple ascending dose (MAD) stage, food-effect and proton pump inhibitor (PPI) stages, and a supplemental drug-drug interaction (DDI) stage.

Timeline

Start
2026-08-28
Primary completion
2027-06-08
Completion
2027-06-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Itraconazole Small molecule — —
Subject RO7890597 Unknown — —
Subject Rabeprazole Small molecule — —

Indications

No indication recorded.