drugset / Trial / NCT07797946
Preoperative Ivabradine Doses for Hemodynamic Stability in FESS
RandomizedParallel-groupQuadruple-blindPrevention
Summary
This study compares two different preoperative doses of a heart-rate-lowering medication called ivabradine in patients undergoing endoscopic sinus surgery under general anesthesia. Patients will receive either a lower dose, a higher dose, or a placebo (inactive pill) before surgery. The goal is to see which approach best keeps blood pressure and heart rate stable during surgery, and whether it reduces bleeding and improves the surge
Timeline
- Start
- 2026-08-01
- Primary completion
- 2027-02-01
- Completion
- 2027-02-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ivabradine | Small molecule | 5 mg | Oral |
| Subject | Ivabradine | Small molecule | 7.5 mg | Oral |
Indications
No indication recorded.