drugset / Trial / NCT07798232
Penicillin to Prevent Early Rheumatic Heart Disease in School-Aged Children
Phase 3
Not yet recruiting
9622 enrolled
Children's Hospital Medical Center, Cincinnati
Murdoch Childrens Research Institute · collabOchsner Health System · collabThe University of Western Australia · collabUganda Heart Institute · collab
RandomizedParallel-groupSingle-blindPrevention
Summary
This study will look at whether children ages 5-8 who take Penicillin V by mouth twice a day are less likely to develop rheumatic heart disease (RHD) over a 3-year period compared to children who do not take the medicine.
Timeline
- Start
- 2027-02-01
- Primary completion
- 2031-07-31
- Completion
- 2032-03-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Penicillin V | Small molecule | 250 mg | Oral |