drugset / Trial / NCT07808515

A Study Comparing Cemiplimab-based Treatments for Adult Participants With Locally Advanced Basal Cell Skin Cancer (laBCC)

NCT07808515 ↗

Phase 2 Not yet recruiting 135 enrolled Regeneron Pharmaceuticals
RandomizedParallel-groupOpen-labelTreatment

Summary

This study will test an experimental Regeneron drug called cemiplimab ("study drug") given alone or in combination with other anti-cancer drugs ("combination treatment") to see if they can help treat laBCC. The study is looking at: * What side effects cemiplimab, alone or in a combination treatment, might cause * How well cemiplimab, alone or in a combination treatment, works * How cemiplimab, alone or in a combination treatment could affect the immune system, which can help researchers understand why cemiplimab, alone or in a combination treatment, works better in some participants than others

Timeline

Start
2026-10-15
Primary completion
2030-11-13
Completion
2030-11-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Cemiplimab Monoclonal antibody — —
Subject Fianlimab Monoclonal antibody — —
Subject Vidutolimod Unknown — —