drugset / Trial / NCT07816341

Phase 1 Study of F182112 in Relapsed/Refractory Autoimmune Hemolytic Anemia

NCT07816341 ↗

Phase 1 Not yet recruiting 12 enrolled Institute of Hematology & Blood Diseases Hospital, China
NaSingle-groupOpen-labelTreatment

Summary

This is an open-label, phase I clinical study of F182112 in patients with relapsed or refractory autoimmune hemolytic anemia (AIHA). Participants will receive F182112 at different dose levels. The main purpose of the study is to evaluate the safety and tolerability of F182112 and to identify an appropriate dose for further clinical development.

Timeline

Start
2026-10-10
Primary completion
2027-12-31
Completion
2028-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject F182112 Monoclonal antibody 30 ug/kg Intravenous
Subject F182112 Monoclonal antibody 90 ug/kg Intravenous
Subject F182112 Monoclonal antibody 180 ug/kg Intravenous