drugset / Trial / NCT07816380

A Phase III Study to Evaluate the Efficacy and Safety of JYP0322 in Previously Untreated ROS1-Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer

NCT07816380 ↗

Phase 3 Not yet recruiting 216 enrolled Guangzhou JOYO Pharma Co., Ltd
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a randomized, open-label, multicenter phase III study to evaluate the efficacy and safety of JYP0322 compared with crizotinib in previously untreated ROS1-positive locally advanced or metastatic non-small cell lung cancer.

Timeline

Start
2026-10-30
Primary completion
2028-12-30
Completion
2029-12-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Crizotinib Small molecule 250 mg Oral
Subject JYP0322 Unknown 150 mg Oral