drugset / Trial / NCT07821177
Bladder Preservation or Cystectomy for MIBC
Non-randomizedParallel-groupOpen-labelTreatment
Summary
In this research study, investigators will assess whether it is feasible to use information from the genes of a tumor combined with evaluation of the tumor response to systemic therapy to determine if bladder sparing chemoradiation can be used or if surgery to remove the bladder, or radical cystectomy, is needed.
Timeline
- Start
- 2026-09-02
- Primary completion
- 2027-09
- Completion
- 2029-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Cisplatin | Other / unclassified | — | Intravenous |
| Background | Gemcitabine | Small molecule | — | Intravenous |
| Background | Mitomycin | Unknown | — | Intravenous |
| Background | fluorouracil | Small molecule | — | Intravenous |