Fractional CO2 Laser vs Dermabrasion With 5-Fluorouracil for Acquired Leukoderma

Summary

This randomized controlled prospective single-blinded comparative clinical study aims to compare the efficacy and safety of fractional carbon dioxide (CO2) laser therapy versus mechanical dermabrasion, both combined with topical 5-fluorouracil, in the treatment of acquired non-vitiligo leukoderma. The study will evaluate repigmentation, clinical improvement, patient satisfaction, and treatment-related adverse effects.

Timeline

Start

2026-08-26

Primary completion

2027-07-26

Completion

2027-08-26

Drugs

Indications