drugset / Trial / NCT07866066

Maridebart Cafraglutide Versus Semaglutide in Participants With Type 2 Diabetes

NCT07866066 ↗

Phase 3 Not yet recruiting 1300 enrolled Amgen
RandomizedParallel-groupOpen-labelTreatment

Summary

The main objective of this trial is to evaluate whether maridebart cafraglutide is non-inferior to semaglutide in improving glycemic control in participants with type 2 diabetes (T2D) who are receiving metformin treatment, with or without a sodium-glucose cotransporter-2 (SGLT-2) inhibitor.

Timeline

Start
2026-11-02
Primary completion
2028-09-04
Completion
2028-12-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Maridebart Cafraglutide Unknown — Subcutaneous
Comparator Semaglutide Peptide — Subcutaneous