drugset / Trial / NCT07866833
Dysfunction of Respiratory Enzymes in Adults With Mental Illness (DREAM)
Non-randomizedCrossoverDouble-blindOther
Summary
This study tested whether intravenous methylene blue changes brain activity during a working-memory task differently in adults with schizophrenia taking stable antipsychotic medication and healthy volunteers. Each participant received methylene blue and a placebo solution with no methylene blue at separate visits and completed the task during functional magnetic resonance imaging (fMRI)
Timeline
- Start
- 2020-06-01
- Primary completion
- 2025-08-31
- Completion
- 2025-08-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methylene Blue | Diagnostic / imaging agent | 0.5 mg/kg | Intravenous |