drugset / Trial / NCT07866833

Dysfunction of Respiratory Enzymes in Adults With Mental Illness (DREAM)

NCT07866833 ↗

Non-randomizedCrossoverDouble-blindOther

Summary

This study tested whether intravenous methylene blue changes brain activity during a working-memory task differently in adults with schizophrenia taking stable antipsychotic medication and healthy volunteers. Each participant received methylene blue and a placebo solution with no methylene blue at separate visits and completed the task during functional magnetic resonance imaging (fMRI)

Timeline

Start
2020-06-01
Primary completion
2025-08-31
Completion
2025-08-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Methylene Blue Diagnostic / imaging agent 0.5 mg/kg Intravenous

Indications