Low Dose Induction for Pediatric Acute Myeloid Leukemia Patients

Summary

the standard induction treatment for pediatric acute myeloid leukemia has high early morbidity and mortality that jeopardize the outcome especially in developing countries. SIOP recommended lower dose induction synergistic G- CSF to minimize these unwanted toxicities. the study aimed at minimizing the toxicities during induction without jeopardizing the survival.

Timeline

Start

2022-07-28

Primary completion

2028-07

Completion

2030-07

Publications

• Results Bansal D, Davidson A, Supriyadi E, Njuguna F, Ribeiro RC, Kaspers GJL. SIOP PODC adapted risk stratification and treatment guidelines: Recommendations for acute myeloid leukemia in resource-limited settings. Pediatr Blood Cancer. 2023 Nov;70(11):e28087. doi: 10.1002/pbc.28087. Epub 2019 Nov 27.

Drugs

Indications